ME - What it IS…

Myalgic Encephalomyelitis (ME, sometimes referred to as ME/CFS) is an acquired and disabling, " serious, chronic, complex, and systemic disease associated with neurological, immunological, autonomic, and energy metabolism dysfunction ". It is classified as a neurological disorder by the World Health Organization (WHO) under ICD-11 Code: 8.E49 (previously ICD-10 G93.3).

• Myalgic Encephalomyelitis (ME) is a disabling, long-term condition
• Estimated to be 2* as common as MS and 3* times more prevalent than HIV/AIDS,
• Clear clinical symptoms which manifest predominantly based on neurological, immunological and endocrinological dysfunction
• Multi-factorial pathogenesis with the hypothesis of initiation by a viral infection prominent.
• Most frequently follows an acute prodromal infection, varying from upper respiratory infections, bronchitis or sinusitis, or gastroenteritis, or an acute “flu-like” illness.
• Before acquiring ME most patients were healthy, leading full and active lifestyles.
• Reaction to physical and mental activity and sensory input is unique to ME.
• Over-exertion can make ME worse and the effects are often delayed and may not be seen within 24 hours.
• Symptoms can range from mild to very severe and can include:
• Cardiac and Cardiovascular Problems
• Cognitive Dysfunction
• Gastro-intestinal Problems
• Headaches
• Hormonal Imbalance
• Immunological Problems
• Muscle Weakness and Intense Pain
• Neurological Problems
• Sleep Problems

What is ME? Guidelines IiMER Leaflet